BACKGROUND: Adherence is the most important factor in
determining Antiretroviral Therapy (ART) treatment success and
long-term viral suppression. Nonadherence to ART led to the
human Immunodeficiency Virus (HIV) related morbidity and
mortality. Moreover, it intensifies the risk of the emerging drug
resistant HIV strains. This study aimed to assess the level of ART
adherence and to identify its predictive associated factors among
people living with HIV/AIDS in Hara Town and its surroundings,
North-Eastern Ethiopia.
METHODS: An institutional facility based cross-sectional study
was conducted from April-May 2017. A total of 454 individuals
were on ART follow-up in the selected ART-clinic, and only 418
patients were recruited. Bivariate and multivariate logistic
regression analyses were carried out to identify associated factors.
Odds ratio and 95% Confidence Interval (CI) were calculated to
determine the level of significance.
RESULTS: The level of ART adherence in the study setting was
300 (71.8%). Participants who had not disclosed their HIV status to
their families were 88% less likely to adhere to their ART
medication than those who had disclosed their HIV status ((Odds
ratio (OR): 0.12, 95%CI:0.05-0.58; p<0.001). On the other hand,
participants who had not encountered drug side effects were
2.69 times more likely to adhere to their ART medication than
those who had ever encountered drug side effects (OR: 2.69,
95%CI:1.27-5.05; p<0.001).

Published: 2019-05-28