BACKGROUND: Diarrheal disease is a major cause of mortality
and morbidity for under-five children in Ethiopia. The purpose of
this study was to investigate the behavioral and socioeconomic risk
factors, etiology, and drug susceptibility of bacteria isolated from
under-five children with acute diarrhea who were treated at Debre
Berhan Referral Hospital or Health Center in Ethiopia.
METHODS: A health facility based cross-sectional study design
was used to investigate enteropathogens from 163 under-five
children with acute diarrhea. After obtaining written consent from
parents or guardians, data were collected using a standardized
questionnaire. Freshly passed stool samples were collected for
microbiological tests for bacteria and parasites. The chi-square test
was used for assessing the relationships of variables.
RESULTS: Enteropathogens were detected among 55.8% (91/163)
participants. There was a 46%(75/163) bacterial culture positivity
rate and a 9.8%(16/163) prevalence of parasites. The isolated
enteropathogens were Escherchia coli, Klebsiella specie, Proteus
species, Salmonella species, Shigella species, Enterobacter species,
Giardia lamblia, Enteameba histolytica, Ascaris lumbricoides,
Trichuris trichiura and Hymnoleps nana. Level of antimicrobial
resistance of bacterial isolates ranged from 0 to 87.2%. Poor hand
washing and poor cleaning of feeding utensils showed significant
association with the presence of enteropathogens.
CONCLUSION: Bacterial enteropathogens with drug resistance
were observed in this study. Continuous health education and
promotion about diarrheal disease for mothers/caretakers and
regular surveillance of entropathogenes are recommended to
reduce under-five mortality. KEYWORDS: Under-five children,
Diarrhea, enteropathogen, drug resistance, Ethiopia

Published: 2019-05-28